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Category: anti-viral drugs
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The bottom line was that after the vaccines rolled out, Trump voting counties saw 40% higher fatality rates per million residents. Before the vaccines, the COVID death rates were the same for all counties.
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I mentioned an experimental drug, molnupiravir that was being developed by Merck and Ridgeback Therapeutics. Well, they just posted an encouraging update. It continues to show success at preventing serious disease when given to high-risk people early after infection.
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What is a world to do? Besides increasing surveillance of viral variants, a couple more prevention initiatives are in the works. One is economic and the other scientific.
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All of this begs two questions; why would vaccines be needed if we had an effective anti-viral drug, and why would a drug be needed if we had an effective vaccine?
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Needed nighttime oxygen for months, still testing positive for COVID-19 antibodies and has permanent lung damage.
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A November 5 preprint showed that a nasal spray was 100% effective in preventing infection in an animal CoV-2 infection model.
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The science around the CoV-2 virus and SpaceX represent the new science world that contrasts to the old science world of hepatitis C and NASA, respectively.
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Being, male, elderly (74 years old), and borderline clinically obese, Trump meets two high-risk criteria for severe COVID-19 disease. Despite reporting negligible symptoms, his doctors at Walter Reed have him on aggressive precautionary therapeutic measures.
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Remember when, at a press conference, Trump turned to some doctors and asked the inelegant question of whether they could use “disinfectants” to treat COVID-19?
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So far, the reports claiming that HCQ is effective against COVID-19 are mostly based on unsubstantiated doctor’s anecdotes, or on uncontrolled retrospective chart reviews. In contrast, the reports that indicate that HCQ is ineffective are based on stronger randomized and controlled clinical trials.
