Making Sense of Medical Science (MSMS)

A medical scientist explains medical news for lay people

Category: mucosal immunity

  • Wouldn’t it be nice if a vaccine could be developed to nip the infection in the bud at the site of entry so it could not set up shop at all? That is an idea behind a mucosal vaccine that I described earlier. This summer, NIH launched the initial Phase 1 trial to begin testing…

  • This was not a meeting called by a regular committee but an ad hoc gathering of some anti-vaccine rogues. It was held in a tiny back room in the Capitol and was poorly attended, poorly staffed, and poorly equipped. It was described as a meeting of the “shadow Congress;” accurately named as it dabbled in…

  • The natural immune response, like the vaccine immune response, is robust and effective, yet both are only directed against a very small portion of a big pathogen, and both are very leaky in that one can still get infected again! What gives?